Includes faculty video presentations and slides Provides detailed information about  target audience, learning objectives, and accreditation Provide faculty disclosure information  and biographies Provides a bibliography of  relevant topics by author Includes instructions and CME  enrollment procedures, CME posttest and evaluation
Contains a PDF version  of the program syllabus


1.
A randomized trial of anticoagulants versus aspirin after cerebral ischemia of presumed arterial origin. The Stroke Prevention in Reversible Ischemia Trial (SPIRIT) Study Group. Ann Neurol. 1997;42:857-865.

2. Albers GW. Choice of endpoints in antiplatelet trials: which outcomes are most relevant to stroke patients? Neurology. 2000;54:1022-1028.

3. Albers GW, Amarenco P. Combination therapy with clopidogrel and aspirin: can the CURE results be extrapolated to cerebrovascular patients? Stroke. 2001;32:2948-2949.

4. Alberts MJ. Diagnosis and treatment of ischemic stroke. Am J Med. 1999;106:211-221.

5. Benavente O, Hart RG, Kent T, et al. Secondary prevention for small subcortical strokes - pilot study [poster]. Poster presented at: American Stroke Association of the AHA 25th International Stroke Conference; February 10-12, 2000; New Orleans, LA.

6. Bhatt DL, Bertrand ME, Berger PB, et al. Meta-analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stenting. J Am Coll Cardiol. 2002;39:9-14.

7. Bhatt DL, Chew DP, Hirsch AT, Ringleb PA, Hacke W, Topol EJ. Superiority of clopidogrel versus aspirin in patients with prior cardiac surgery. Circulation. 2001;103:363-368.

8. Bhatt DL, Hirsch AT, Ringleb PA, Hacke W, Topol EJ, on behalf of the CAPRIE investigators. Reduction in the need for hospitalization for recurrent ischemic events and bleeding with clopidogrel instead of aspirin. Am Heart J. 2000;140:67-73.

9. Bhatt DL, Kapadia SR, Bajzer CT, et al. Dual antiplatelet therapy with clopidogrel and aspirin after carotid artery stenting. J Invasive Cardiol. 2001;13:767-771.

10. Boysen G, Truelsen T. Prevention of recurrent stroke. Neurolog Sci. 2000;21:67-72.

11. Brass LM. Advances in long-term stroke prevention with antiplatelet therapy. Journal of Stroke and Cerebrovascular Diseases. 2001;10:18-23.

12. Brass LM, Lichtman JH, Wang Y, Gurwitz JH, Radford MJ, Krumholz HM. Intracranial hemorrhage associated with thrombolytic therapy for elderly patients with acute myocardial infarction: results from the Cooperative Cardiovascular Project. Stroke. 2000;31:1802-1811.

13. CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet. 1996;348:1329-1339.

14. Chaturvedi S, Hickenbottom S, Levine SR. Ischemic stroke prevention. Curr Treat Options Neurol. 1999;1:113-126.

15. Chew DP, Bhatt DL, Robbins MA, et al. Effect of clopidogrel added to aspirin before percutaneous coronary intervention on the risk associated with C-reactive protein. Am J Cardiol. 2001;88:672-674.

16. CURE Study Investigators. The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme; rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease. Eur Heart J. 2000;21:2033-2041.

17.
De Schryver ELLM. Design of ESPRIT: An international randomized trial for secondary prevention after non-disabling cerebral ischaemia of arterial origin. Cerebrovasc Dis. 2000;10:147-150.

18. Diener H-C. Management of atherothrombosis with clopidogrel in high-risk patients with recent TIA or ischaemic stroke (MATCH): rationale and study design [poster]. Poster presented at: European Stroke Conference; May 17, 2001; Lisbon, Portugal.

19.
Easton JD. Current advances in the management of stroke. Neurology. 1998;51(suppl 3):S1-S2.

20. Easton JD. What have we learned from recent antiplatelet trials? Neurology. 1998;51(suppl 3):S36-S38.

21. Easton JD. Future perspectives for optimizing oral antiplatelet therapy. Cerebrovasc Dis. 2001;11(suppl 2):23-28.

22. Goldstein LB, Bian J, Samsa GP, Bonito AJ, Lux LJ, Matchar DB. New transient ischemic attack and stroke: outpatient management by primary care physicians. Arch Intern Med. 2000;160:2941-2946.

23.
Gorter JW, for the Stroke Prevention In Reversible Ischemia Trial (SPIRIT) and European Atrial Fibrillation Trial (EAFT) Study Groups. Major bleeding during anticoagulation after cerebral ischemia: patterns and risk factors. Neurology. 1999;53:1319-1327.

24.
Hennessy MJ, Britton TC. Transient ischaemic attacks: evaluation and management. Int J Clin Pract. 2000;54:432-436.

25. Johnston SC, Gress DR, Browner WS, Sidney S. Short-term prognosis after emergency department diagnosis of TIA. JAMA. 2000;284:2901-2906.

26. Leys D. Atherothrombosis: a major health burden. Cerebrovasc Dis. 2001;11(suppl 2):1-4.

27. McCabe DJ, Brown MM. Prevention of ischaemic stroke-antiplatelets. Br Med Bull. 2000;56:510-525.

28. McDonald CT, Koroshetz WJ. Transient ischemic attack and secondary stroke. Curr Treat Options Neurol. 2000;2:329-342.

29. Mohr JP, Thompson JLP, Lazar RM, et al. A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke. N Engl J Med. 2001;345:1444-1451.

30. Oddone E, Brass LM, Booss J, et al. Quality enhancement research initiative in stroke: prevention, treatment, and rehabilitation. Med Care. 2000;38:I92-I104.

31. Sarasin FP, Gaspoz J-M, Bounameaux H. Cost-effectiveness of new antiplatelet regimens used as secondary prevention of stroke or transient ischemic attack. Arch Intern Med. 2000;160:2773-2778.

32. Yusuf S, Reddy S, Ounpuu S, Anand S. Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization. Circulation. 2001;104:2746-2753.

33. Yusuf S, Reddy S, Ounpuu S, Anand S. Global burden of cardiovascular diseases: part II: variations in cardiovascular disease by specific ethnic groups and geographic regions and prevention strategies. Circulation. 2001;104:2855-2864.

34.
Yusuf S, Zhao F, Mehta SR, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345:494-502.


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